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MassZymes 250 caps

MassZymes Digestive Enzyme Supplement for Women and Men (250 caps)

Crank Your Muscle Gains To New Heights By Transforming 1 Gram Of Protein Into 3 Grams with the best supplement for digestive problems

  • Increase your absorption of key amino acids
  • Stronger, Healthier Digestion
  • Boost your absorption of certain vitamins
  • Increase your mental clarity and focus
  • Repair damaged intestinal wall
  • Decreases need for sleep and recovery
  • Contains 100,000 HUTs of protease per capsule

$75 or $62/month

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MassZymes Nutritional Facts

  • Designed to aid digestion and support digestive issues
  • Breaks down fats, starches and sugars
  • Increases energy
  • Promotes good brain health
  • Replaces naturally-occurring processing, irradiation and cooking
  • Improves assimilation and utilization of food into amino acids that assist with not only overall health but brain health as well
  • Eliminates brain fog

Suggested Use

Designed to be taken with meals and protein shakes.Take 3 capsules with each meal. May take 1-3 capsules with each meal and 1-2 capsules in between the meals. Store in a cool / dry location.

Product Certifications

Made in the USA

MassZymes FAQ’s:

1. When is the best time to take MassZymes?

Systemic enzymes are taken on an empty stomach as digestion will interfere with their effectiveness. We suggest you take our Masszymes first thing in the morning on an empty stomach, or during the day to elicit a systemic enzymatic effect. To improve digestion take Masszymes a few minutes before each meal of the day. **Please Note: Our enzymes can be used both for food digestion and on an empty stomach as well. When you take our MassZymes on an empty stomach they become metabolic. If you take them with the food they become digestive.

2. Are enzymes dangerous?

No! The enzymes we recommend are perfectly safe to consume. Some people with gastritis or ulcers may not be able to consume them. But be sure to consult your health professional and ask him/her if enzymes are safe for you to use.

3. Are all enzymes created equal?

No. Most brands sold in stores only work at a very narrow PH level, which means they get destroyed during the digestive process. Our Full Spectrum enzymes work at a PH range between 2 and 12, which maximizes its digestive effects. Plus our supplement is the most powerful protease supplement on the market. Also, due to the high protease count in our MassZymes, this can actually help reduce strength loss, and boost short-term strength recovery too when you train.
Here is the scientific proof:

4. Why do you use RICE BRAN in this product?

We use stabilized hypoallergenic rice bran as an agent to prolong the shelf life of the enzymes which can become activated by moisture. By including a stabilized hypoallergenic rice bran we are able to offer longer shelf life and improved effectiveness of the product.

5. Does Masszymes (Digestive Enzymes) only digest protein?

No...our enzymes not only break down protein but also carbohydrates, fats & sugars. The Protease in our enzymes breaks down protein. The Amylase in our enzymes breaks down carbohydrates and Lipase breaks down fats in our body.

6. Are these vegan and cruelty-free?

Yes, they are. The capsules are cellulose (Wade the co-founder is vegetarian). The enzymes are fermented using plants.

7. Can children take this product? If so, what is the recommended dosage?

Yes, children can take this product. Give them 1 capsule every 44 lbs body weight.

8. Can I empty the contents in the capsule in a beverage?

Yes, you can empty the contents of this product in your beverage of choice.

9. Is it okay for pregnant or breastfeeding women to take this product?


10. What is the recommended dosage?

You can follow the recommended dosage on the label, but Wade Lightheart (co-founder/creator of the BiOptimizers product line) suggests 3 Levels you can follow while taking this product. Please see this document for more details.

Enzymes Supplement FAQ’s:

What are the digestive enzymes?

Digestive enzymes are proteins that break down foods in your digestive tract into smaller units that can be absorbed into your bloodstream. 

These enzymes are produced by your salivary glands, the secretory cells in the stomach and small intestines, and the pancreas. If the enzymes are produced outside of the gut, it’s in the pro-enzyme forms that become activated once it reaches inside the gut. For example, pepsins, a protein-digesting enzyme, are produced and secreted as pepsinogens before the stomach acid activates it. 

Enzymes can also come along with your foods, such as cellulase in fermented foods, bromelain in pineapple, and papain in papaya. The enzymes in raw foods is why fruits can be used in marinades to tenderize meat. 

What are the main digestive enzymes?

Digestive enzymes can be broken down into groups based on what they digest, including:

  • Proteases, which digest proteins into short snippets (peptides)
  • Peptidases, which digest peptides into amino acids
  • Amylase and diastase, which digest starch
  • Invertase, which breaks down sucrose (table sugar) into glucose and fructose
  • Lactase, which breaks down lactose into glucose and galactose
  • Lipase, which breaks down fats into fatty acids and glycerol
  • Alpha-galactosidase can break down the gas-inducing sugars from legumes and some vegetables without creating the gas
  • Phytase, which breaks down phytic acid and improves the absorption of minerals
  • Cell wall-digesting enzymes, such as hemicellulase, beta-glucanase, and pectinase. Beta-glucanase specifically helps break down the cell walls of yeasts and bacteria, and their biofilms. 
  • Systemic enzymes, such as bromelain and the enzymes in AstraZymeTM, which are special proteases that can get absorbed into the bloodstream
What are protease enzymes used for?

Proteases can help you digest proteins, so your body can use the amino acids. Incompletely digested proteins can cause food allergies or sensitivity. High-quality proteases also improve the quality or availability of amino acids from plant-based proteins, which is why Wade relied on MassZymes for his plant-based bodybuilding career. Other bodybuilders also find that they need less protein for the same results once they take MassZymes.

Some proteases, like bromelain and the enzymes in Astrazyme, can get absorbed into the bloodstream. These enzymes promote healthy tissue healing and balanced immune responses. One study showed that systemic enzymes improved strength in people who were less strength-trained. It also improved the inflammatory, metabolic, and immune responses to training, which aids in recovery. 

How do you fix your digestive system?

To optimize your digestion and reduce bloating, it is important to:

  • Eat slowly and mindfully. Chew your food well and don’t eat distracted.
  • You may find certain foods to be a trigger for indigestion and other digestive symptoms. You want to avoid these foods.
  • Manage stress.
  • Eat a healthy diet
  • Eat enough fiber and good fats

MassZymes can help you optimize your enzyme levels in a meal, whereas HCl Breakthrough can ensure that you have enough stomach acid. P3OM and Leaky Gut Guardian are designed to help optimize digestion and gut barrier health by ensuring a healthy microbiome. Gluten Guardian can also help break down proteins that are difficult to digest and tend to trigger inflammation, such as gluten and casein. 

If you have a digestive condition, first consult your physician for medical advice.

What are the common diseases of the digestive system?

Common digestive disorders include:

  • Bloating, belching, and gas, which often arise from poor digestion and an overgrowth of bacteria in the small intestine
  • Acid reflux or Gastroesophageal Reflux Disease (GERD), caused by low stomach acid and an overgrowth of bacteria in the small intestine that produce gas in the gut
  • Irritable bowel syndrome, such as constipation, diarrhea, or a combination of both. It can be caused by food allergies, stress, reduced gut movement, or small intestine bacterial overgrowth.
  • Food allergies and sensitivities may result in non-digestive symptoms, but these start from poor digestion, leaky gut, and immune imbalance.
  • Post-meal fatigue, which is also caused by poor digestion and sometimes inflammation from food sensitivities
  • Celiac disease is an autoimmune disease where the immune system confuses gluten with an invader, causing the immune system to attack the small intestine. 
  • Inflammatory Bowel Diseases are a group of autoimmune disorders where the gut immune system confuses food or the gut bacteria for pathogens. 
What can cause digestive problems?

Many factors can cause or trigger a digestive disorder, including:

  • Stress
  • Food allergy, insensitivities, or intolerances
  • Unhealthy eating habits, such as eating distracted or in a hurry
  • Unhealthy diet lacking fiber, micronutrients, omega-3, and antioxidants
  • Autoimmunity, an imbalance in your immune system that causes your body to attack itself, such as Celiac disease or inflammatory bowel disease. 
  • Nutrient deficiencies, such as zinc and vitamin D
  • Infections, such as Helicobacter pylori and parasites
  • Imbalances in gut bacteria (dysbiosis) caused by stress, unhealthy diet, infections, and chronic inflammation. Dysbiosis can cause digestive symptoms and negative effects on all other aspects of health. 
  • Leaky and inflamed gut lining, reducing digestive enzymes and protective mucus
When should I be concerned about digestive problems?

Your gut is the interface where all your nutrients come into your body. Also it is where 80% of your immune system and much of your nervous system reside. If your goal is to optimize health, aesthetic, and performance, then you should always keep your digestion optimized.

Symptoms of poor digestion are not normal and should always be addressed. If your digestion is optimal, food will simply take away hunger; you will not feel a heavy stomach, bloating, pain, or fatigue after meals.

MassZymes Related Links

Product Dimensions

  • Cap diameter: 1.5 inches
  • Bottom diameter: 2.5 inches
  • Height: 5 inches
  • Weight: 5 ounces


Do not use if ulcer or gastritis are present.

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Biohackers, Doctors, Scientists, Health And Fitness Leaders Who Love BiOptimizers

Mr. Leslie M. Hudson
Masszymes & probiotics for healthy gut flora
April 9, 2018

Size: 250 Verified Purchase

I'm so happy I discovered this product. I believe enzymes can help with all manner of problems and you cannot take too many. The recommended dosage is based on a healthy 150 pound male. Once your body uses the enzymes to break down and digest food, the body will put any excess to work in other places. I researched Enzymes when my dad was diagnosed with Stage IV Pancreatic Cancer. We started him on megadoses of BiOptimizers Masszymes, along with probiotics. He lived twice as long as doctors thought he would. Excruciation abdominal pain and trouble eating solid food is typical with Stage IV Pancreatic cancer. Dad ate up until a few days before he died, and he never experienced pain at all. Several other family members have had acid and bloating issues and were taking acid reducers. Since stomach acid declines as we age, there is no need for people to take acid reducers, in fact they do more harm then good. We stopped the acid reducers and started taking Masszymes & probiotics daily to help maintain healthy gut flora.
Masszymes are my favorite enzymes!
September 4, 2018

Size: 250 Verified Purchase

I happily have taken Masszymes for a few years, both with food and on an empty stomach before bed to get a cleansing detox overnight. Their overall higher dosage seems true after I compared amounts in several other popular enzyme formulas. For some months I took three bottles a month for accelerated cleansing, but now I am on the maintenance dose of one bottle a month. I plan to use Masszymes for years to come. The company's customer service is top-notch.
Work as proteolytic enzyme, much less joint pain and swelling.
April 5, 2018

Size: 250 Verified Purchase

Love this product. Use it as proteolytic enzyme. Take 5 in AM empty stomach and 5 before bed empty stomach. This helps tremendously for my RA swelling and pain. I hope it will keep the inflammation in bay so my joints can heal.
Zoe L. Martell
Best enzymes ever!
November 13, 2018

Size: 250 Verified Purchase

I have taken a lot of digestive enzymes over the years, with little result.... until these! Honestly, the whole BiOptimizers line is fantastic. I use the enzymes, the HCL, and the probiotic .... and they are the only ones I will buy from now on. I've wasted a lot of money on digestive products that do nothing, and buying lower priced products is just not worth it. I am a huge fan of these products and I will continue to use them.


If you're not happy with MassZymes for any reason anytime between today and 365 days from now, we'll refund you the full amount you paid for shipping. No questions asked. Our customer happiness team will take complete care of you.

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